Pertactin oor Duits
Pertactin
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Pertactin
In that context, Medeva further stresses that it has produced no vaccine containing only FHA and pertactin. (26)
In diesem Zusammenhang hebt Medeva zudem hervor, dass sie keinen Impfstoff hergestellt habe, der nur FHA und Pertactin enthalte(26).
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pertactin
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A highly immunogenic virulence factor of Bordetella pertussis, a bacterium that causes pertussis.
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In support of those applications, Medeva submitted MAs granted by the French, German and United Kingdom authorities for medicinal products named Infanrix DTCaP, Infanrix IPV, Infanrix IPV+HIB, Infanrix Quinta, Pediacel and Repevax, each of which contained, in addition to the combination of pertactin and filamentous haemagglutinin, other active ingredients, the total number of which was between 8 and 11.
Betrifft: Durchführbarkeitsstudie, Fußgängersicherheit und EEVC-PrüfungEurLex-2 EurLex-2
Pertussis toxoid# Filamentous Haemagglutinin# Pertactin# Hepatitis B surface antigen# Poliovirus (inactivated
Einschränkung der Verwendung der Einrichtung (soweit zutreffendEMEA0.3 EMEA0.3
Pertussis toxoid#, Filamentous haemagglutinin#, Pertactin#) Hepatitis B surface antigen# Poliovirus (inactivated) type #, #, # Haemophilus type b polysaccharide (polyribosylribitol phosphate
Willst du deinen Vater töten?EMEA0.3 EMEA0.3
In the case of the fifth application (SPC/GB09/018), the Patent Office concluded inter alia that, although the active components or ingredients identified in the patent were the same as those specified in the SPC application, namely the combination of pertactin and filamentous haemagglutinin, the MAs submitted in support of that application did not fulfil the conditions laid down in Article 3(b) of the Regulation, inter alia because they related to medicinal products containing 9 active ingredients, that is to say vaccines which did not contain only the active components or ingredients specified in the SPC application and in the patent claims.
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In that context, Medeva further stresses that it has produced no vaccine containing only FHA and pertactin. (26)
Die derzeitigen Verkaufszahlen betreffend diese beiden Endverwendungszwecke werden niedrig bzw. auf Null veranschlagtEurLex-2 EurLex-2
Patent claim 1 reads as follows: ‘A method for the preparation of an acellular vaccine, which method comprises preparing the 69kDa antigen of Bordetella pertussis [= pertactin] as an individual component, preparing the filamentous haemagglutinin antigen of Bordetella pertussis as an individual component, and mixing the 69kDa antigen and the filamentous haemagglutinin antigen in amounts that provide the 69kDa antigen and the filamentous haemagglutinin antigen in a weight ratio of between 1:10 and 1:1 so as to provide a synergistic effect in vaccine potency.’
SONSTIGE BESTANDTEILEEurLex-2 EurLex-2
13 On 26 April 1990, Medeva filed an application for a European patent, registered by the European Patents Office (EPO) under EP number 1666057, for a method for the preparation of an acellular vaccine against Bordetella pertussis (whooping cough agent), also known as ‘Pa’, consisting of a combination of two antigens as active ingredients, namely pertactin and filamentous haemagglutinin (‘filamentous haemagglutinin antigen’), in such a ratio as to provide a synergistic effect in vaccine potency.
Ein Unternehmen, das bisher IAS # (überarbeitet #) angewandt hat, hat die mitdiesem Standard vorgenommenen Änderungen entweder retrospektiv auf alle Leasingverhältnisse oder, bei keiner retrospektiven Anwendung von IAS # (überarbeitet #), auf alle Leasingverhältnisse anzuwenden, die seit der erstmaligen Anwendung dieses Standards abgeschlossen wurdenEurLex-2 EurLex-2
The 4 th dose resulted in a pronounced boost with 9 (fimbriae type 2) to 24-fold (pertactin) titer rises.
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It was concluded that the Polish whole cell pertussis vaccine stimulates antibodies against pertussis toxin, FHA and pertactin, but that antibodies against FHA probably also are stimulated by cross-reacting antigens.
Vielen Dankspringer springer
Antibodies were determined against pertussis toxin, filamentous hemagglutinin (FHA), pertactin, tetanus toxoid and diphtheria toxin.
Das Licht ging anspringer springer
SPC applications 09/016 and 09/018 concern multi‐disease vaccines with eleven active ingredients, whereas SPC application 09/016 relates to the antigens pertactin and FHA and seven further active ingredients and SPC application 09/018 only to the antigens pertactin and FHA.
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SPC application 09/018 is also the only application which relates only to the active ingredients pertactin and FHA which are used in the process described in the basic patent.
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Pertussis toxoid#, Filamentous haemagglutinin#, Pertactin#) Hepatitis B surface antigen# Poliovirus (inactivated) type
Ferner werden die Pläne nicht berücksichtigt, nach denen das Enfopol-Abhörsystem in der EU vorangetrieben werden soll.EMEA0.3 EMEA0.3
40 However, it should be added that, in a situation such as that in the main proceedings, first, only the authorisation in respect of the first medicinal product placed on the European Union market comprising, among its active ingredients, the combination of the two active ingredients identified in the wording of the claims of the patent, namely pertactin and filamentous haemagglutinin, may be regarded as the first MA for that ‘product’ as a medicinal product within the meaning of Article 3(d) of Regulation No 469/2009.
Quantitative ereignisspezifische Methode auf Basis der Polymerase-Kettenreaktion in Echtzeit für genetisch veränderten GA#-MaisEurLex-2 EurLex-2
As active ingredients it contained the antigens pertactin, FHA and pertussis toxin, in combination with diphtheria toxoid and tetanus toxoid so as to be effective against whooping cough, diphtheria and tetanus.
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Aim of the study was to evaluate reactogenicity and immunogenicity of a monovalent, acellular 4-component pertussis vaccine (pertussis toxin = PT, filamentous haemagglutinin = FHA, pertactin, fimbriae-type 2) when given as a booster dose after primary immunization with the same vaccine.
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