The present invention describes a novel synthesis method for the preparation of compounds of general formula 3 and also novel synthesis intermediates, which comprises the following steps: obtaining compound 4-amino-2-(phenylamino)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one (21) by means of a multicomponent reaction between an alkyl acrylate (18), malononitrile (19) and phenylguanidine carbonate (20); and brominating the compound (21) to give 4a-bromo-2-(4-bromophenylamino)-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-4(4aH)-iminium bromide (a Wheland intermediate (1)), which is heated in DMSO to give the intermediate 4-amino-6-bromo-2-(4-bromophenylamino)pyrido[2,3-d]pyrimidin-7(8H)- one (2).
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