Protein Z oor Spaans
Protein Z
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Proteína Z
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Protein Z is a member of the coagulation cascade, the group of blood proteins that leads to the formation of blood clots.
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The diet has to contain exactly x grams of fat, y grams of protein and z grams of carbohydrates.
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Factor IXa, in turn, forms a complex with Factor VIIIa (FIXa-FVIIIa) and activates factor X. Inhibitors of factor XIa include protein Z-dependent protease inhibitor (ZPI, a member of the serine protease inhibitor/serpin class of proteins), which is independent of protein Z (its action on factor X, however, is protein Z-dependent, hence its name).
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The sarcomeres are separated from each other by dense zig-zagging protein-based structures called Z discs.
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Several human Gla-containing proteins synthesized in several different types of tissues have been discovered: Coagulation factors (II, VII, IX, X), as well as anticoagulation proteins (C, S, Z).
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Through a multi-disciplinary approach, MUZIC project partners set out to generate a comprehensive spatio-temporal picture of the muscle Z-disk protein complexes.
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The z chain is a transmembrane protein belonging to a multimeric complex in association with the T-cell receptor (TCR).
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Extending longitudinally on either side of the Z line are strands of a thin protein, actin (see Fig. 23.3g).
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It is not yet known whether anticoagulant therapy or prophylaxis is indicated in protein Z or ZPI deficiency.
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Protein Z Deficiency - Hematology and Oncology - MSD Manual Professional Edition
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Protein Z Deficiency - Hematology and Oncology - Merck Manuals Professional Edition
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Other coagulation factors dependent on vitamin K are protein C, protein S, and protein Z; proteins C and S are anticoagulants.
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Introduction.The T-cell receptor (TCR)-associated complex, CD3 (d, g, e) and z-chains are essential transmembrane proteins for signal transduction during T cell activation and immune response, as well as during thymocyte development.
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Other tests associated with APS are assays to detect antibodies against prothrombin, protein S, protein C, protein Z, annexin V and factor XIII.
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NSC4492 treatment showed no effect on the self-assembly and budding of virus-like particles (VLPs) but an alteration in the electrophoretic pattern of protein Z and a strong inhibition of viral RNA synthesis were evidenced.
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And we say partially because dicoumarines affect the formation of procoagulant factors II, VII, IX and X, and protein C, protein S and protein Z inhibitors; while DOAC inhibit the activity of thrombin (dabigatran) or activated factor X (rivaroxaban, apixaban, edoxaban).
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Other clotting factors that depend on vitamin K are protein C, protein S, and protein Z. Deficiency of vitamin K or disturbances of liver function (for example, severe liver failure) may lead to deficiencies of clotting factors and excess bleeding.
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The consequence of protein Z or ZPI deficiency, or of autoantibodies to protein Z, in the pathophysiology of thrombosis and fetal loss is not completely clear; however, either defect may make thrombosis more likely if an affected patient also has another congenital coagulation abnormality (eg, factor V Leiden).
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When dividing subjects into two groups according to their body mass index, overweight participants show higher Z-score cardiovascular risk values, pulse wave velocity, log of the triglyceride/protein ratio and the Δ pulse wave velocity (p > 0.001).
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It is interesting that the most important role of protein Z is the degradation of the activated factor X that is produced by a protease inhibitor, the action of which is accelerated 1000 times by the presence of the protein Z[1,2], and the deficiency of protein Z (as protein C and S deficit) would be linked to pro-thrombotic states[3] and late fetal losses[4,5].
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Z p53 Protein Antigen Background This monoclonal antibody recognizes both wild type and mutant forms of...
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Z AFP A protein normally produced by a fetus.
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Z CD134 A protein being studied in the treatment of cancer.
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Also depicted in the image above is a second disk-like protein aggregate: the M-line, which is centrally located in sarcomeres. Like proteins of the Z disc, the proteins of the M line (M band) act as an embedding matrix, in this case for the myosin thick filaments.
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68 sinne gevind in 21 ms. Hulle kom uit baie bronne en word nie nagegaan nie.