adenylic acid oor Spaans
adenylic acid
en
(organic chemistry) A nucleotide found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. It consists of a phosphate group, a pentose sugar ribose, and the nucleobase adenine.
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ácido adelínico
ácido adenílico
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Then, polyadenylation occurs by the sequential addition of adenylic acid residues (Step 4).
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The tRNA–amino acid–adenylate complex is next attached to the mRNA template, a process that occurs in the ribosomes.
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An adenylate moiety is then transferred to form nicotinic acid adenine dinucleotide (NaAD).
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Cells activate carboxylic acids by converting them into acyl phosphates, acyl adenylates, or thioesters.
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In the first step, the amino acid is activated by formation of a reactive aminoacyl-adenylate intermediate.
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Translate "adenylic acid" to Spanish: ácido adenílico
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Translate "ácido adenílico" to English: adenylic acid
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The synthetase first binds ATP and the corresponding amino acid (or its precursor) to form an aminoacyl-adenylate, releasing inorganic pyrophosphate (PPi).
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Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA.
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First is the adenylation of the amino acid, which forms aminoacyl-AMP: amino acid + ATP ↔ aminoacyl-AMP + PPi Second, the amino acid residue is transferred to the tRNA: aminoacyl-AMP + tRNA ↔ aminoacyl-tRNA + AMP The net reaction is: amino acid + ATP + tRNA ↔ aminoacyl-tRNA + AMP + PPi The net reaction is energetically favourable only because the pyrophosphate is hydrolysed; that reaction is highly energetically favourable and drives the other reactions.
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All this degradation of the glucids is done in the presence of an enzyme that is formed by the pyrophosphates of adenylic acid in the presence of magnesium salts.
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It is a ß-adrenergic blocking agent which stimulates adenylate cyclases, protein kinases and the breakdown of triglycerides in free fatty acids and glycerol, promoting the breakdown of fats.
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The adenylate-aaRS complex then binds the appropriate tRNA molecule's D arm, and the amino acid is transferred from the aa-AMP to either the 2'- or the 3'-OH of the last tRNA nucleotide (A76) at the 3'-end.
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It can activate adenylate kinase, increase brain ATP/ADP ratio, and increase brain absorption and utilization of amino acids, proteins and glucose. Promotes brain cell metabolism.
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