alfaxalone oor Spaans

alfaxalone

naamwoord
en
A neurosteroid general anaesthetic used in veterinary medicine.

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Alfaxalona

en
chemical compound
es
compuesto químico
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Alfaxalone works as a positive allosteric modulator on GABAA receptors and, at high concentrations, as a direct agonist of the GABAA receptor.
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In cats, there is a greater production of 20-hydroxyalfaxalone sulfate than alfaxalone glucuronide; cats also have 3β-alfaxalone-sulfate, which is not present in dogs.
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Alfaxalone is also a derivative of allopregnanolone, differing from it only by the addition of the C11 ketone.
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A 3:1 mixture of alfaxalone with alfadolone acetate that previously had been used as a general anesthetic.
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