biotransformation mechanism oor Spaans
biotransformation mechanism
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mecanismo de biotransformación
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However, because biotransformation mechanisms were not well investigated, it is generally not possible to extrapolate predictions of biotransformation potential beyond the specific sites investigated.
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Distribution, rather than excretion or biotransformation, is the dominant mechanism influencing plasma clearance
Diámetro interno: mmEMEA0.3 EMEA0.3
(b) adaptation of the organism to the load with regard to the pharmacological target organs or the biotransformation enzymes or the excretory mechanisms;
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Mycoremediation is the technology based on the natural biotransformation mechanisms of fungi to convert residues, that might be considered as toxic for humans, into harmless molecules that may then be released to nature.
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Then, in order to study such mechanism and explore the capacity of this fungus to biotransform trans-cinnamic acid into value-added products, the microorganism was incubated with the substrate using three different culture media (Czapeck-Dox, Sabouraud and PDB) at room conditions.
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Studies examining the toxicokinetics (TK) of a test chemical are conducted to obtain adequate information on its absorption, distribution, biotransformation (i.e. metabolism) and excretion, to aid in relating concentration or dose to the observed toxicity, and to aid in understanding its mechanism of toxicity.
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Due their extreme toxicity, they represent a hostile environment for microbial colonization; however, there are metalotolerant bacteria in these mining wastes, and this is attributed to mechanisms of bioaccumulation and biotransformation of metals.
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This course presents the principles of environmental toxicology, including the major classes of toxicants, environmental movement and fate, toxicokinetics, biotransformation, toxicodynamics, factors influencing toxicity, mechanisms of toxic action and detoxication, mutagenicity and carcinogenicity, toxicity testing and evaluation, and risk assessment.
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Environmental Toxicology This course presents the principles of environmental toxicology, including the major classes of toxicants, environmental movement and fate, toxicokinetics, biotransformation, toxicodynamics, factors influencing toxicity, mechanisms of toxic action and detoxication, mutagenicity and carcinogenicity, toxicity testing and evaluation, and risk assessment.
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Nonetheless, phenolic compounds bioaccessibility and biotransformation is often not considered in these studies; thus, a precise mechanism of action of phenolic compounds is not known.
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TERMS AND DEFINITIONS Pharmacology related terms Drug related terms Dose related terms PHARMACOLOGY RELATED TERMS Pharmacology is the science that embraces the knowledge of the history, source, physical and chemical properties, compounding, biochemical and physiological effects, mechanism of action, absorption, distribution, biotransformation and excretion of drugs.
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Biotransformation and mineralization of pollutants present in the water are carried out by physical, chemical, biochemical, and microbiological mechanisms.
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It is used in CHEMICAL FRACTIONATION of proteins.Pharmacokinetics: Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM.
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It has only been in the last decade that the genetics of the cytochromes has been explored and that the mechanisms underlying some therapeutic interactions and aspects of drug metabolism have been uncovered, making it possible to characterize the biotransformation pathway of amodiaquine and chloroquine.
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Also, I aim to study the contribution of plasmatic metabolites to the development of cardiovascular diseases and to highlight the molecular mechanism of action by studying the aorta and heart proteome. In addition, my goal was to study the biotransformations that occur in the digestive tract as a consequence of microbial metabolisms and the potential activity against colon cancer.
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Prospection of active molecules based on purely chemical analysis followed by bioassays, the test of only species of traditional medicine or chemotaxonomic approach gave way to more current strategies seeking more effectiveness than in the past, and have given way to bioassay-guided isolation, generation of libraries of natural products, dereplication, metabolomic approaches and biotransformation in the effort to identify molecules that allow us to understand mechanisms of plant defense and apply this knowledge to elucidate molecular mechanisms and discover structures applicable in the therapeutic or phytosanitary protection, to name only two very motivating areas of scientific efforts.
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Prospection of active molecules based on purely chemical analysis followed by bioassays, the test of only species of traditional medicine or chemotaxonomic approach gave way to more current strategies seeking more effectiveness than in the past, and have given way to bioassay-guided isolation, generation of libraries of natural products, dereplication, metabolomic approaches and biotransformation in the effort to identify molecules that allow us to understand mechanisms of plant defense and apply this knowledge to elucidate molecular mechanisms and discover structures applicable in the therapeutic or phytosanitary protection, to name only two very motivating areas of scientific efforts.
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Prospection of active molecules based on purely chemical analysis followed by bioassays, the test of only species of traditional medicine or chemotaxonomic approach gave way to more current strategies seeking more effectiveness than in the past, and have given way to bioassay-guided isolation, generation of libraries of natural products, dereplication, metabolomic approaches and biotransformation in the effort to identify molecules that allow us to understand mechanisms of plant defense and apply this knowledge to elucidate molecular mechanisms and discover structures applicable in the therapeutic or phytosanitary protection, to name only two very motivating areas of scientific efforts.
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The native bacteria from El Fraile mine tailings have developed adaptation mechanisms that allow them to persist in a toxic environment, thus, the objective of this study was to isolate and identify bacteria with the ability to tolerate, bioaccumulate or biotransform heavy metals.
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This study examines impact of arsenic speciation, especially As (III), on the environment and health as well as the biochemical mechanisms involved in the microbial oxidation of arsenite to reduce its toxicity, aiming to develop clean environment friendly strategies for removing arsenic from contaminated water and soil. Keywords: arsenite; arsenate; arsenite oxidase; biotransformation.
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20 sinne gevind in 10 ms. Hulle kom uit baie bronne en word nie nagegaan nie.