crizotinib oor Spaans

crizotinib

naamwoord
en
An aminopyridine drug used to treat certain kinds of lung carcinoma.

Vertalings in die woordeboek Engels - Spaans

Crizotinib

en
chemical compound
es
compuesto químico
wikidata

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Advanced filtering
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About 5% of these have activating rearrangements of the alk gene and may respond to crizotinib.
los cristales de insulina protamina se disuelven a un pH ácidoLiterature Literature
Crizotinib is now approved in the United States for treatment of NSCLCs. * Choi, S.M., et al. 2007.
Phelps... en nombre de mis queridos amigos Alfred y Carlotta Bowan "Literature Literature
ROS1 rearranged lung cancers also respond to crizotinib with response rates over 70%.
El cálculo de la demanda media individual no debe tener en cuenta los años en que la empresa respectiva no haya utilizado sustancias reguladas como agentes de transformaciónLiterature Literature
At 1 year, however, resistance develops in most patients taking crizotinib.
Periodista Lydig, segunda víctimaLiterature Literature
Crizotinib is another type of small-molecule tyrosine kinase inhibitor that is used to treat non-small cell lung cancer.
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You may take crizotinib with or without food.
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In a small clinical trial, the drug crizotinib shrank tumors in children with cancers that have alterations in the ALK gene.
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Two other ALK inhibitors, brigatinib and ensartinib (also called X-396), are currently being tested against crizotinib in clinical trials as first-line treatments for ALK-positive NSCLC.
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A study (NCT00585195) that screened 1,500 patients with NSCLC for ALK rearrangements identified 82 patients with advanced ALK-positive disease who were enrolled in a clinical trial that was an expanded cohort study instituted after phase I dose escalation had established a recommended dose of crizotinib dual and ALK inhibitor of 250 mg bid in 28-day cycles.
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The goal of the trials is to determine whether erlotinib or crizotinib will prevent lung cancer recurrence, as well as prolong life, when used against tumors that carry specific mutations.
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These drugs include: Crizotinib Alectinib
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Intended Use The Vysis ALK Break Apart FISH Probe Kit is a qualitative test to detect rearrangements involving the ALK gene via fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded (FFPE) non-small cell lung cancer (NSCLC) tissue specimens to aid in identifying those patients eligible for treatment with Xalkori® (crizotinib).
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In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “Crizotinib Shows Promise for Childhood Cancers was originally published by the National Cancer Institute.”
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First, the researchers identified a dose of crizotinib that could be safely used in children, and then they assessed the ability of crizotinib to shrink tumors in patients with alterations in the ALK gene who had the potential to benefit.
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That appears to be the case for alectinib, as it prevented new cancer metastases in the brain and central nervous system better than crizotinib.
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Crizotinib, if patients have not already received it
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Crizotinib comes in a capsule form and is taken twice a day.
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Patients with theses ROS1 rearrangements have shown increased positive responses to crizotinib, an oral ALK inhibitor.
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Crizotinib was originally approved for patients with advanced NSCLC whose tumors have similar alterations in the ALK gene.
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At 12 months after initiating treatment, 67% of patients treated with brigatinib were still alive without any evidence of their cancer getting worse, compared with 43% of those treated with crizotinib.
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ALK mutation analysis is used primarily to determine if a person with adenocarcinoma non-small cell lung cancer is likely to respond to an ALK kinase inhibitor drug therapy, such as crizotinib.
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The following side effects are common (occurring in greater than 30%) for patients taking Crizotinib:
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What SPECIAL PRECAUTIONS should I follow? Before taking crizotinib,
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For tumors that have the ALK gene change, crizotinib (Xalkori) is often the first treatment.
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A second phase II, open-label trial enrolled 138 patients with ALK-positive stage IIIB/IV NSCLC who had disease progression on crizotinib.
El intervalo entre inyecciones debe ser de al menos un mesParaCrawl Corpus ParaCrawl Corpus
212 sinne gevind in 9 ms. Hulle kom uit baie bronne en word nie nagegaan nie.