gliotoxin oor Spaans
gliotoxin
en
A mycotoxin, originally isolated from Gliocladium fimbriatum, that causes apoptosis of certain cells
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Gliotoxina
en
chemical compound
es
compuesto químico
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voorbeelde
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Gliotoxin content: max. 50 μg/kg in the technical grade of the MCPA.
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Gliotoxin possesses immunosuppressive properties that may suppress and cause apoptosis in certain cells of the immune system, including neutrophils, eosinophils, granulocytes, macrophages, and thymocytes.
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For instance, it cannot fully explain how gliotoxin causes apoptotic and necrotic death of animal cells.
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In the process of development Trichoderma synthesizes a variety of antibiotics (gliotoxin, viridine, trichodermin and others).
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The best-known ETP is gliotoxin, which appears to be a virulence factor associated with invasive aspergillosis of immunocompromised patients.
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Interest in gliotoxin as a therapeutic agent was initiated when it was shown to prevent viral RNA replication, via inhibition of reverse transcriptase (De Clercq et al., 1978; Rightsel et al., 1964).
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For example, the eurotiomycete Aspergillus fumigatus produces gliotoxin, but other Aspergillus spp.
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Gliotoxin has also been reported from yeasts of the genus Candida, [2] but results from other studies have cast doubt on the production of this metabolite by Candida fungi.
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In the process of development Trichoderma synthesizes a variety of antibiotics (gliotoxin, viridine, trichodermin and others).
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The ANT is sensitive to oxidizing agents and has two cysteine residues which may be targets of gliotoxin (McStay et al., 2002).
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20 sinne gevind in 9 ms. Hulle kom uit baie bronne en word nie nagegaan nie.