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Interchromosomal translocations are most easily detected by spectral karyotyping.
Randy Price, Beau MungerLiterature Literature
Cis-duplication, or intrachromosomal duplication, entails the duplication of genes within the same chromosome whereas trans duplication, or interchromosomal duplication, consists of duplicating genes on neighboring but separate chromosomes.
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On the other hand, when using a repair inhibitor, such as ara-C, interchromosome differences in the capacity of excision repair were detected.
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Four interchromosomal abnormalities, including the previously known ALK and DUSP22-IRF4 translocations
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The second model, Interchromosomal network (ICN model), suppose, on the contrary, the existence of recovering zones between neighbor territories, in which the chromatin fibers of the two chromosomes are closely associated.
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Jan, 2008 | Pubmed ID: 18202363 Intra- and interchromosomal interactions have been implicated in a number of genetic phenomena in diverse organisms, suggesting that the higher-order structural organization of chromosomes in the nucleus can have a profound impact on gene regulation.
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In the model based on the localization of some genes, transcripts are released into interchromosomal channels, transferred to sites for processing, then exported to the cytoplasm after maturation.
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