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Neurotrophin-3, or NT-3, is a neurotrophic factor, in the NGF-family of neurotrophins.
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BDNF was the second neurotrophic factor to be characterized, after NGF and before neurotrophin-3.
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NGF nerve growth factor; BDNF brain-derived neurotrophic factor; NT-3 neurotrophin-3.
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The neurotrophic factors used were epidermal growth factor (EGF), fibroblast growth factor-2 (FGF-2), nerve growth factor (NGF), neurotrophin-3 (NT-3), and ciliary neurotrophic factor (CNTF).
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«Neurotrophin-3: a neurotrophic factor related to NGF and BDNF».
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BDNF is the second neurotrophic factor to be characterized, after NGF and before neurotrophin-3.
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A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3.
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NT-3 is unique among the neurotrophins in the number of neurons it has potential to stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB).
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It is widely expressed in nervous tissue and may play a role in mediating the effects of NEUROTROPHIN 3 on the proliferation and differentiation of NEURONS.
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By increasing the production of a protein called neurotrophin-3 (NT3), they were able to reverse hearing loss in mice that had been partially deafened by loud noise.
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By increasing the production of a protein called neurotrophin-3 (NT3), they were able to reverse hearing loss in mice that had been partially deafened by loud noise.
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Researchers discovered that by increasing the production of a protein, neurotrophin-3 (NT3), they could reverse hearing loss in mice that had been partially deafened by loud noise.
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Neurotrophins (NGF, BDNF, NT-3, NT-4/5) and their receptors (the Trks and p75) are present and active in retina of several species and they have been identified as an importantd molecules of eye development.
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NT-3 is unique in the number of neurons it can potentially stimulate, given its ability to activate two of the receptor tyrosine kinase neurotrophin receptors (TrkC and TrkB - see below).
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The thesis is divided into 4 chapters: 1) study of neurotrophins in ASD, where the results show the relationship of this family of molecules with the disease, 2) study of Latrophilin-3 (LPHN3) in the TEA, which was obtained in association with lower
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