relaxation of vascular smooth muscle oor Spaans
relaxation of vascular smooth muscle
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relajación del músculo liso vascular
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A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cyt
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Vasodilation is a result of both direct relaxation of vascular smooth muscle and α blockade.
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It causes relaxation of vascular smooth muscle by a cyclic AMP-dependent mechanism.
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However, with respect to vasculature, activation of M3 on vascular endothelial cells causes increased synthesis of nitric oxide, which diffuses to adjacent vascular smooth muscle cells and causes their relaxation and vasodilation, thereby explaining the paradoxical effect of parasympathomimetics on vascular tone and bronchiolar tone.
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The normal pulmonary endothelial cell maintains the vascular smooth muscle in a state of relaxation.
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The researchers found that taurine depletion increases contractility but decreases the relaxation of vascular smooth muscle.
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Magnesium has a direct effect on the relaxation of vascular smooth muscle and the regulation of ions important to blood pressure control.
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The mechanism of the antihypertensive action of amlodipine is due to a direct relaxant effect on vascular smooth muscle, causing reductions in peripheral vascular resistance and in blood pressure
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It relaxes vascular smooth muscle by binding to the haeme moiety of cytosolic guanylate cyclase, activating guanylate cyclase and increasing intracellular levels of cyclic guanosine #-monophosphate, which then leads to vasodilation
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During sexual stimulation, Ll lation, nitric oxide (NO) released from nonadrenergic, noncholinergic (NANO) neurons and endothelial cells stimulates guanylate cyclase to produce cGMP, which in turn decreases intracellular calcium levels. This ultimately results in the relaxation of the vascular smooth muscle and increased blood flow into the corpus cavernosa, followed by penile erection (8,9).
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It relaxes the vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter.
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Nitric oxide causes the increase of blood vessels lumen by relaxing smooth muscles and reduction of the 'viscosity' of vascular wall, thereby increasing the supply of oxygen and nutrients to the working muscles.
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They are located in the smooth muscles of the blood vessels, as well as in the lungs. Because the M3 receptor is Gq-coupled and mediates an increase in intracellular calcium, it typically causes contraction of smooth muscle, such as that observed during bronchoconstriction and bladder voiding.[20] However, with respect to vasculature, activation of M3 on vascular endothelial cells causes increased synthesis of nitric oxide, which diffuses to adjacent vascular smooth muscle cells and causes their relaxation, thereby explaining the paradoxical effect of parasympathomimetics on vascular tone and bronchiolar tone.
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The mechanism of the antihypertensive action of amlodipine is due to a direct relaxant effect on vascular smooth muscle, causing reductions in peripheral vascular resistance and in blood pressure.
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The main function is to improve the function of nerve cells, adjust the transmission of nerve impulses, enhance memory function, due to its strong lipotropy, absorbed quickly through the blood brain barrier into the brain, help relax vascular smooth muscle cells, increase the role of brain blood flow.
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The main function is to improve the function of nerve cells, adjust the transmission of nerve impulses, enhance memory function, due to its strong lipotropy, absorbed quickly through the blood brain barrier into the brain, help relax vascular smooth muscle cells, increase the role of brain Methyl-Testos terone Test Acetate
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All four groups of animals exhibited a similar dose-dependent relaxation in response to SNP (Figure 1), supporting no influence on vascular smooth muscle function as well as POX-related effects centered on endothelial cell function.
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19 sinne gevind in 25 ms. Hulle kom uit baie bronne en word nie nagegaan nie.