relaxin receptor oor Spaans
relaxin receptor
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receptor de relaxina
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Relaxin receptors have been found in the heart, smooth muscle, the connective tissue, and central and autonomous nervous system.
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Relaxin interacts with the relaxin receptor LGR7 (RXFP1) and LGR8 (RXFP2), which belong to the G protein-coupled receptor superfamily.
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These effects of relaxin are thought to be mediated by interactions between endothelin type B receptors and NO. Thus, relaxin appears to play an important role in many of the cardiovascular adaptations of pregnancy via NO-dependent mechanisms. PREGNANCY AND HEART DISEASE
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