selective autophagy oor Spaans
selective autophagy
Vertalings in die woordeboek Engels - Spaans
autofagia selectiva
en
macroautophagy process in which specific structures are targeted by the autophagy process
Geskatte vertalings
Vertoon algoritmies gegenereerde vertalings
voorbeelde
Advanced filtering
Voorbeelde moet herlaai word.
He is speaker of the Collaborative Research Center 1177 on selective autophagy, and speaker of the LOEWE program "Ubiquitin Networks".
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He expanded his research to the field of selective autophagy, recognizing the enormous impact of the LC3/GABARAP signaling network displaying striking mechanistic similarities to ubiquitin.
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Results indicated that infection of primary human monocytes with Aspergillus spores triggered selective recruitment of the autophagy protein LC3 II.
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The selective autophagy works as a quality control for removing organelles which are not working properly.
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The relationship of AtMC1 and NBR1 (involved in selective autophagy) has also been studied, suggesting an indirect homeostatic defect in the atmc1 mutant with consequences in selective autophagy.
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Taken together, we demonstrate that in mammalian cells under mild oxidative stress a DRP1-dependent type of mitophagy is triggered while a concomitant induction of non-selective autophagy was not observed.
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EMBO Reports selects a study by researchers at IRB Barcelona as the highlighted article of the week because of the relevance of autophagy in health.
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To limit the growth of their offspring and ensure the continuity of intracellular infection, the bacteria themselves take advantage of a process called aggrephagy (type of selective autophagy that eliminates protein aggregates useless to the cell) which culminates with the sacrifice of only some members of its progeny.
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The network also foresees the divulging and transfer of the results to the society that will go since recommendations for a healthy aging or for the prevention of illnesses, until the discovery of new therapies or the development of biocomponents or nanodevices to modulate the autophagy selectively.
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However, co-evolution between host-cells and pathogens has selected numerous infectious invading microorganisms able to avoid or usurp autophagy to their own benefit.
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In particular, they demonstrated that melanoma cells limit ATG5 levels in a very specific way: by selectively losing one of the copies of this gene; a process that does not occur in relation to other autophagy factors.
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Identifying and developing (in preclinical models) novel therapeutic approaches for the treatment of brain tumors and other tumor types based on (i) the use of selective drugs for molecular targets involved in the resistance to cannabinoids and other antitumor drugs (ii) the stimulation of autophagy mediated death.
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The LID mice have a selective liver deficiency in IGF-1 gene that results in a lower IGF-1 plasma level than in control mice. Our results showed that nutritional stress by serum/glucose deprivation stimulated an early and progressive autophagy in primary cultures of neonatal rat cardiac myocytes, as determined by the processing of endogenous protein LC3-I. This effect was not observed in cardiac myocytes exposed to nutritional stress by serum/aminoacid deprivation.
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13 sinne gevind in 12 ms. Hulle kom uit baie bronne en word nie nagegaan nie.