xenobiotic metabolism oor Spaans
xenobiotic metabolism
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metabolismo xenobiótico
Following oral administration, octaBDE is an inducer of xenobiotic metabolism with dose and time dependent relationship.
Tras la administración oral, el octaBDE es un inductor del metabolismo xenobiótico que depende de la relación entre la dosis y el tiempo transcurrido.
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Following oral administration, octaBDE is an inducer of xenobiotic metabolism with dose and time dependent relationship.
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Better understanding of microbiome-encoded pathways for xenobiotic metabolism also has important implications for improving the efficacy of pharmacologic interventions with neuromodulator agents.
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Xenobiotics are metabolized in two phases.
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A, Xenobiotics can be metabolized to nontoxic metabolites and eliminated from the body (detoxification).
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(d) the capacities to metabolize xenobiotic compounds differ widely between organisms and between test systems.
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A variety of factors may affect the activities of the enzymes involved in metabolizing xenobiotics.
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Cyclic gene expression in the various organs governs overt rhythms in behavior and physiology, encompassing sleep-wake cycles, metabolism, xenobiotic detoxification, and cellularproliferation.
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This enzyme participates in metabolism of xenobiotics by cytochrome p450.
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It is convenient to consider the metabolism of xenobiotics in two phases.
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The electrophoresis technique was used to study the activity of esterase isozymes involved in the metabolism of xenobiotics of A. niger , combined with changes in the expression of isozymes after contamination by pesticides.
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Xenobiotic metabolism Antibiotic resistance
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They do not readily undergo degradation by xenobiotic metabolizing enzymes (XMEs), because of their bulk and halogenation.
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The decreases in xenobiotic metabolism shown with carbon monoxide exposure might be important to individuals receiving treatment with drugs.
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POPs cannot be metabolized by the xenobiotic metabolizing system and therefore tend to accumulate in ecosystems and in living organisms.
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In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms.
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Enzymes such as CYP3A4, along with the antiporter activities, are also instrumental in the intestine's role of drug metabolism in the detoxification of antigens and xenobiotics.
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Describe the two phases of xenobiotic metabolism, the first involving mainly hydroxylation reactions catalyzed by cytochromes P450 and the second conjugation reactions.
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They noted that “involvement of numerous pathways associated with lipid and xenobiotic metabolism raises serious concerns about potential drug interactions as well as the safety of CBD.”
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Functions that can be evaluated postnatally include neurological development, simple and complex behaviours, reproduction, endocrine function, immune competence, xenobiotic metabolism and physiological function of different organ systems.
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Louisa Hooven and colleagues, in a paper published by PLoS ONE, detail how circadian rhythms coordinate xenobiotic metabolizing genes, or genes responsible for breaking down toxic substances such as pesticides.
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The objective of the project is to evaluate the association between the different genetic polymorphisms found on genes involved in xenobiotic metabolism in patients at risk of developing an oral cancer.
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In humans, at least 18 families and 44 xenobiotic metabolizing CYP450 subfamilies have been described, of which only the CYP1, CYP2 and CYP3 families appear to be important in drug metabolism.
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A number of phases occur once the drug enters into contact with the organism, these are described using the acronym LADME: Liberation of the active substance from the delivery system, Absorption of the active substance by the organism, Distribution through the blood plasma and different body tissues, Metabolism that is inactivation of the xenobiotic substance, and finally Excretion or elimination of the substance or the products of its metabolism.
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