drug dependence oor Galisies
drug dependence
Vertalings in die woordeboek Engels - Galisies
drogadicción
en
substance dependence that involves the continued use of drugs despite problems related to use of the substance
Geskatte vertalings
Vertoon algoritmies gegenereerde vertalings
voorbeelde
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In 1985 the World Health Organization's Expert Committee on Drug Dependence recommended that MDMA be placed in Schedule I of the 1971 United Nations Convention on Psychotropic Substances.
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Warfarin and related drugs inhibit vitamin K-dependent carboxylation of several coagulation factors, including prothrombin.
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Both characters play instruments (House plays the piano, the guitar, and the harmonica; Holmes, the violin) and take drugs (House is dependent on Vicodin; Holmes uses cocaine recreationally).
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During the sessions, Bowie was heavily dependent on drugs, especially cocaine, and later claimed that he recalled almost nothing of the production.
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The relative effectiveness of IRS versus other malaria control techniques (e.g. bednets or prompt access to anti-malarial drugs) varies and is dependent on local conditions.
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In addition, there are some tissues (such as the brain tissue) that present a real barrier to the distribution of drugs, that can be breached with greater or lesser ease depending on the drug's characteristics.
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Treatment is usually performed together with other chemotherapy drugs (such as cytarabine), and its administration depends on the type of tumor and the degree of response.
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Two other types of acquired resistance rarely seen include the production of drug-inactivating enzymes (esterases or kinases), as well as the production of active ATP-dependent efflux proteins that transport the drug outside of the cell.
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We totally depend on what we call "post-marketing surveillance," after the drugs hit the market.
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This new concept builds on earlier ideas and it depends on a number of distinct factors: The drugs characteristics, including its pKa.
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The final outcome of the transformations that a drug undergoes in an organism and the rules that determine this fate depend on a number of interrelated factors.
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For this reason the effect on the cell is dose dependent; the fraction of cells that die is directly proportional to the dose of drug.
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Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+ biosynthesis.
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Notwithstanding this, the relationship between the drug-mediated depolymerization of microtubules and the specific expression of transcription factors has been described, which has provided information on the differential expression of the genes depending on the presence of these factors.
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A variety of cellular changes can trigger gating, depending on the ion channel, including changes in voltage across the cell membrane (voltage-gated ion channels), drugs or hormones interacting with the ion channel (ligand-gated ion channels), changes in temperature, stretching or deformation of the cell membrane, addition of a phosphate group to the ion channel (phosphorylation), and interaction with other molecules in the cell (e.g., G proteins).
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The «renal clearance» rate will be determined by factors such as the degree of plasma protein binding as the drug will only be filtered out if it is in the unbound free form, the degree of saturation of the transporters (active secretion depends on transporter proteins that can become saturated) or the number of functioning nephrons (hence the importance of factors such as renal failure).
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16 sinne gevind in 11 ms. Hulle kom uit baie bronne en word nie nagegaan nie.