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genetic drift

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(genetics, evolutionary theory) An overall shift of allele distribution in an isolated population, due to random fluctuations in the frequencies of individual alleles of the genes.

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variation in the relative frequency of different genotypes in a small population
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This loss or fixation of the gene proceeds based on random sampling known as genetic drift.
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This change is due to four different processes: mutation, selection (natural and artificial), gene flow and genetic drift.
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This is due to a sampling effect, and is called genetic drift.
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Genetic drift was embraced as an additional mechanism of evolutionary development in the modern synthesis of the theory.
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Theoretically, it is unlikely that genetic drift would render vaccines and antivirals against SARS-CoV-2 ineffective quickly.
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Hence, in this model, most genetic changes in a population are the result of constant mutation pressure and genetic drift.
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The process of genetic drift can be illustrated using 20 marbles in a jar to represent 20 organisms in a population.
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Ford's work would contribute to a shift in emphasis during the course of the modern synthesis towards natural selection over genetic drift.
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The time for a neutral allele to become fixed by genetic drift depends on population size, with fixation occurring more rapidly in smaller populations.
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Genetic divergence will always accompany reproductive isolation, either due to novel adaptations via selection and/or due to genetic drift, and is the principal mechanism underlying speciation.
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This fluctuation is analogous to genetic drift – a change in the population's allele frequency resulting from a random variation in the distribution of alleles from one generation to the next.
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In addition to founder effects, the new population is often a very small population, so shows increased sensitivity to genetic drift, an increase in inbreeding, and relatively low genetic variation.
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Where Simpson relied upon a synergistic interaction between genetic drift and a shift in the adaptive fitness landscape, Eldredge and Gould relied upon ordinary speciation, particularly Ernst Mayr's concept of allopatric speciation.
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Even in the absence of selective forces, genetic drift can cause two separate populations that began with the same genetic structure to drift apart into two divergent populations with different sets of alleles.
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The American biologist Sewall Wright, who had a background in animal breeding experiments, focused on combinations of interacting genes, and the effects of inbreeding on small, relatively isolated populations that exhibited genetic drift.
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They suggest the divergence of the Denisova mtDNA results either from the persistence of a lineage purged from the other branches of humanity through genetic drift or else an introgression from an older hominin lineage.
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In 1932, Wright introduced the concept of an adaptive landscape and argued that genetic drift and inbreeding could drive a small, isolated sub-population away from an adaptive peak, allowing natural selection to drive it towards different adaptive peaks.
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The effective population size (Ne) is defined as "the number of breeding individuals in an idealized population that would show the same amount of dispersion of allele frequencies under random genetic drift or the same amount of inbreeding as the population under consideration."
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By 1969, Motoo Kimura and others provided a theoretical basis for the molecular clock, arguing that—at the molecular level at least—most genetic mutations are neither harmful nor helpful and that mutation and genetic drift (rather than natural selection) cause a large portion of genetic change: the neutral theory of molecular evolution.
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