Some minor physical anomalies are typical. These include flat occiput, high and rounded forehead with pronounced metopic ridge, mild ptosis, epicanthal folds, elongated face, enlarged nose root with rounded nose tip and anteverted nostrils, long philtrum, low-set ears with voluminous lobes and prominent anthelix, microretrognathia, short neck; and more rarely, lymphedema of the back of hands and feet.
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