whereas nitrogen oxide emissions, especially in port cities and coastal areas, are to a large extent generated by shipping and are a major concern for public health and environmental protection in Europe; whereas overall nitrogen oxide emissions from shipping in the EU remain largely unregulated and it is estimated that if left unabated they will surpass land-based nitrogen oxide emissions as early as 2020 (20);
Disturbi oftalmici che sono stati raramente osservati con interferoni alfa includono retinopatie (incluso edema maculare), emorragie retiniche, ostruzioni arteriose o venose retiniche, macule visive, diminuzione dell' acuità visiva o del campo visivo, nevrite ottica e papilledema (vedere paragrafoEurlex2019 Eurlex2019