More particularly, the present invention relates to an AMPK-activating compound comprising one of the 2,5-bis-aryl-3,4-dimethyltetrahydrofuran lignan-based compounds produced by extracting Myristica fragrans with a solution of 30% or less of ethanol and separating and purifying the extracts using chromatography, as expressed in chemical formula 1 below, and to a composition comprising same as an active ingredient for preventing and treating metabolic syndrome-related diseases caused by AMPK enzyme activation, such as obesity, diabetes, high cholesterol and cardiopulmonary diseases.
본 발명의 병마개는 기밀부와 둘레부를 구비한다. 기밀부는 병의 개구부에 삽입되어 개구부를 밀봉하고, 둘레부는 기밀부의 상측 연부로부터 하향 연장형성되어 개구부의 외주면을 감싸도록 형성된다.patents-wipo patents-wipo