A composition for preventing or treating immunological rejection containing lyposomal coenzyme Q10 and FK-506 as active ingredients, according to the present invention, addresses the issues of insolubility and stability exhibited the existing coenzyme Q10, and thus can maximize the pharmacological effect thereof, and as the treatment is in tandem with the FK-506 compound, the adverse effects associated with the FK-506 compound can be minimized, and thus immunological rejection, such as transplant rejection, can be highly effectively prevented or treated, and as cytotoxicity does not arise, drug toxicity and adverse effects are absent, and thus can be taken safely long-term.
본 발명에서 제공하는 리포좀 형태의 코엔자임 Q10 및 FK- 506 화합물을 유효성분으로 포함하는 조성물은 종래 코엔자임 Q10의 불용성 문제 및 안정성 문제를 해결하여 코엔자임 Q10이 가지고 있는 약리학적 효과 를 극대화시킬 수 있고, FK— 506 화합물이 갖는 부작용을 최소화 시킬 수 있다.patents-wipo patents-wipo