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graft-versus-host disease

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Using blood donated by family members, says the Red Cross report, can trigger GVHD (Graft- Versus- Host Disease), a disorder that occurs when the lymphocytes in transfused blood attack the bone marrow, liver, and skin of the recipient.
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In addition, the composition of the present invention can alleviate the weight loss caused by inflammatory bowel disease, regulate the activity of IgG of pathogenic B cells, inhibit the expression of inflammatory cytokines, and remarkably increase the activity of Foxp3+ Treg, and thus can be useful as a composition for preventing or treating various immune diseases such as inflammatory bowel disease, lupus, graft-versus-host disease and the like.
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Graft versus-host disease can occur when the donor's cells are recognized by the patient's (host's) body as foreign.
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To prevent graft-versus-host disease and graft rejection, medications are usually given to the patient for the first 3-6 months following transplantation.
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Our latest research is focused on eliminating graft-versus-host disease in transplant patients, and reducing the risk of MDS developing into leukemia. Browse through some of our clinical trials and research projects.
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In addition to standard therapies, City of Hope's active clinical trials program is testing new treatments for MDS, including identifying new potential targets for new drugs, therapies designed to reduce the risk of graft-versus-host disease in transplant patients, and reducing the risk of MDS developing into leukemia.
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Enhance bone marrow/stem cell transplants: While stem cell transplants can be a lifesaving procedure for leukemia patients, they also carry a risk of graft-versus-host disease (GvHD), in which the newly transplanted stem cells do not recognize the recipient's body as their own and start producing an immune response against it, leading to chronic and potentially serious complications.
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Enhance bone marrow/stem cell transplants: While stem cell transplants can be a lifesaving procedure for patients with AML, they also carry a risk of graft-versus-host disease (GvHD), in which the newly transplanted stem cells do not recognize the recipient's body as their own and start producing an immune response against it, leading to chronic and potentially serious complications.
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