primaquine oor Portugees

primaquine

naamwoord
en
A medication used in the treatment of malaria and Pneumocystis pneumonia.

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Primaquina

naamwoord
en
chemical compound
pt
composto químico
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If the G6PD level is normal, a 14-day course of primaquine is given.
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Chemoprophylaxis of malaria—Primaquine has been studied as a daily chemoprophylactic agent.
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Here's your primaquine.
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Primaquine is especially effective in preventing a relapse from the latent forms of P. vivax in the liver.
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Primaquine.
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Glucose 6-phosphate dehydrogenase activity should be estimated before giving primaquine.
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Only the 8-aminoquinolines (e.g. primaquine and tafenoquine) have this action.
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In any event, primaquine should be discontinued if there is evidence of hemolysis or anemia.
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The pharmacology of primaquine and similar drugs has been reviewed by Shanks et al. (2001).
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Patients should be tested for G6PD deficiency before primaquine is prescribed.
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Chemistry & Pharmacokinetics Primaquine phosphate is a synthetic 8-aminoquinoline (Figure 52–2).
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Treatment of P. vivax requires both treatment of blood stages (with chloroquine or ACT) and clearance of liver forms with primaquine.
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He was successfully treated with primaquine and chloroquine.
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As with chloroquine, eradication of P vivax and P ovale requires a course of primaquine. 2.
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An antimalarial drug such as primaquine is believed to act by causing oxidative stress to the parasite.
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Eradication of P vivax and P ovale requires a course of primaquine to clear hepatic stages. 3.
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Primaquine does not affect sporozoites and has little if any action against the erythrocytic stage of the parasite.
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The patient gradually improved and was treated with primaquine to prevent relapse.
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Primaquine is widely distributed to the tissues, but only a small amount is bound there.
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Pharmacokinetics: Primaquine is well absorbed after oral administration and is not concentrated in tissues.
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All Plasmodium species may develop resistance to primaquine.
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Etaquine and tafenoquine are more active and slowly metabolised analogues of primaquine.
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Two patients who were unable to take primaquine received only chloroquine, and had not relapsed 18 months later.
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The drug primaquine treats the dormant liver parasites, to prevent relapses.
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Two enzimopenic patients had not experienced the symptoms of hemolysis during prior treatment with primaquine at 0.50 mg/kg/day for 7 days.
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