tropical spastic paraparesis oor Portugees
tropical spastic paraparesis
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Paraparesia espástica tropical
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The patient was diagnosed with myelopathy associated with HTLV-1/tropical spastic paraparesis and treated with interferon beta-1a.
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In addition to causing a form of adult leukemia, the virus has also been linked to a nerve disease —tropical spastic paraparesis, or TSP— that is similar to multiple sclerosis.
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The disease was clinically established as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and laboratory tests confirmed the presence of antibodies to HTLV-1 in the cerebrospinal fluid (CSF). Mumps, cytomegalovirus, Epstein-Barr virus, schistosomiasis, herpes virus 1 and 2, rubella, measles, varicella-zoster toxoplasmosis, hepatitis, HIV, and syphilis were excluded by serology.
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CD4+ T cell subsets changes in HTLV-1-infected subjects with tropical spastic paraparesis...
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Tropical spastic paraparesis (TSP) is a chronic degenerative neurological disease associated with this infection.
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Two major diseases are related to this virus adult T cell leukemia (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
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The diagnosis of tropical spastic paraparesis/HTLV-1–associated myelopathy is usually based on symptoms and the person’s risk of being exposed to the virus.
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The main HTLV-1-associated diseases are the HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and the adult T cell leukemia/lymphoma (ATL)....
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Two major pathologies has been associated with HTLV-1 infection: adult T- cell leukemia/lymphoma (ATLL) and HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM / TSP).
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However, a low number of individuals with tropical spastic paraparesis and associated myelopahy to the HTLV-I (TSP/HAM) show immunopathologic characteristics as T lymphocytes proliferation.
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izabela_stmAbstract Human T-lymphotropic virus 1 (HTLV-1) is associated with Tropical Spastic Paraparesis / HTLV-1 Associated Myelopathy (HAM / TSP), a disease characterized by slow and progressive evolution.
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In addition to the well-known association between HTLV-1 and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), several diseases and neurologic manifestations have been associated with the virus.
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Resumen: The HTLV-1 was first described retroviruses associated with human diseases, such as leukemia adult T cell (ATLL), tropical spastic paraparesis / HTLV-associated myelopathy (TSP / HAM), infective dermatitis, among others.
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INTRODUCTION: the HTLV-1 is a human retrovirus associated with adult T-cell leukaemia (ATL) and with HTLV-1- associated myelopathy or tropical spastic paraparesis, which has also been implicated in the development of autoimmunity.
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Syrinx of the Spinal Cord and Brain Stem Tropical Spastic Paraparesis/HTLV-1–Associated Myelopathy Causes of spinal cord disorders include injuries, infections, a blocked blood supply, and compression by a fractured bone or a tumor.
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For example, blood tests may be done to rule out Lyme disease, syphilis, AIDS, tropical spastic paraparesis, and lupus, and imaging tests can help rule out arthritis of the neck, rupture of a spinal disk, and syringomyelia.
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The human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes a persistent infection, in which the majority of patients remains asymptomatic while about 0.5 to 5% of infected individuals develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
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In order to determine the prevalence of ocular lesions in HTLV-1 infected patients in Salvador Bahia, a transversal study was conducted on 140 HTLV-1 infected patients (90 asymptomatic and 50 tropical spastic paraparesis/HTLV-1-associated myelopathy) between June 2004 and November 2005.
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Other tests can help doctors distinguish multiple sclerosis from disorders that cause similar symptoms, such as AIDS, tropical spastic paraparesis, vasculitis, arthritis of the neck, Guillain-Barré syndrome, hereditary ataxias, lupus, Lyme disease, rupture of a spinal disk, syphilis, and a cyst in the spinal cord (syringomyelia).
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