The capsaicin and piperine, found in black pepper and chili peppers, are made up of larger, heavier molecules called alkylamides, and those mostly stay in your mouth.
The massive attention the Chili Peppers started receiving, however, caused Frusciante to feel extremely uncomfortable, and he abruptly quit the band during the Japanese leg of the album's tour.
The ensuing tour was extremely profitable; the Chili Peppers performed three concerts in London's Hyde Park to over 250,000 attendees and a total gross accumulation of US$17.1 million.