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disulfide bond

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(organic chemistry) A bond, consisting of a covalent bond between two sulfur atoms, formed by the reaction of two thiol groups, especially between the thiol groups of two proteins

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Anti-bfgf humanized double-stranded antibody with stable disulfide bond, preparation method and application thereof
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Disclosed are an anti-bFGF humanized double-stranded antibody with stable disulfide bond, preparation method and applications thereof.
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By site-directed mutation, one cysteine residue is introduced into each single-stranded antibody, thus introduce the disulfide bond and form ds-Diabody.
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A disulfide species is a particular pairing of cysteines in a disulfide-bonded protein and is usually depicted by listing the disulfide bonds in parentheses, e.g., the "(26–84, 58–110) disulfide species".
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CD79 is composed of two distinct chains called CD79A and CD79B (formerly known as Ig-alpha and Ig-beta); these form a heterodimer on the surface of a B cell stabilized by disulfide bonding.
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Related to 1 and 2, the disulfide bond link two segments of the protein chain, the disulfide bond increases the effective local concentration of protein residues and lowers the effective local concentration of water molecules.
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Provided in the present invention is a reagent for improving the performance of a reverse transcriptase, and the major constituent of the reagent is a sulfhydryl blocking agent or a disulfide bond-reducing agent or a mixture thereof.
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A disulfide bond is typically denoted by hyphenating the abbreviations for cysteine, e.g., when referring to ribonuclease A the "Cys26–Cys84 disulfide bond", or the "26–84 disulfide bond", or most simply as "C26–C84" where the disulfide bond is understood and does not need to be mentioned.
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Molecules on neighboring keratin strands can form a disulfide bond , in which two sulfur atoms are covalently bonded together.
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When the two disulfide bond formation in large, gluten dough will form a huge network, thereby enhancing its taste.
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Since the cytosol contains high concentrations of glutathione and is, therefore, a reducing environment , proteins containing disulfide bonds , which are formed from oxidized cysteine residues, cannot be produced within it.
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However, proteins can become cross-linked, most commonly by disulfide bonds , and the primary structure also requires specifying the cross-linking atoms, e.g., specifying the cysteines involved in the protein's disulfide bonds.
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NADP also supports the sulfhydryl system, and the balance of reduced glutathione and sulfhydryl-disulfide protein bonds system, which controls the state of the electrons of the cells and influences the hydrophobicity and the hydrophilicity.
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The compound adopts a hexagonal crystalline structure similar to molybdenum disulfide. Every tungsten atom is covalently bonded to six selenium ligands in a trigonal prismatic coordination sphere while each selenium is bonded to three tungsten atoms in a pyramidal geometry. The tungsten–selenium bond has a length of 0.2526 nm, and the distance between selenium atoms is 0.334 nm.
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Molybdenum disulfide lubricant has good dispersion, non-adhesive advantages, can be added in a variety of oils and fats to form non-bonded colloidal state, which can increase lubrication and extreme pressure of grease.
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15 sinne gevind in 5 ms. Hulle kom uit baie bronne en word nie nagegaan nie.