In 1891, the English physician George Redmayne Murray introduced subcutaneously injected sheep thyroid extract,[60] followed shortly after by an oral formulation.[6] [61] Purified thyroxine was introduced in 1914 and in the 1930s synthetic thyroxine became available, although desiccated animal thyroid extract remained widely used. Liothyronine was identified in 1952.[6]
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