Metadata
Author: patents-wipo
Data
English[en]
The purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative of the present invention effectively regulates the activity of B-raf kinase, and thus may be useful for preventing or treating cancer induced by the over-activation of Raf kinase, especially various melanoma, colorectal cancer, prostate cancer, thyroid cancer, ovarian cancer and the like.
French[fr]
Le dérivé de purinylpyridinylamino-2,4-difluorophényl sulfonamide de la présente invention régule efficacement l'activité de la B-raf kinase, et par conséquent peut être utile pour la prévention ou le traitement d'un cancer induit par la suractivation de la Raf kinase, en particulier divers mélanomes, un cancer colorectal, un cancer de la prostate, un cancer de la thyroïde, un cancer ovarien et similaires.
Korean[ko]
본 발명에 의한 퓨리닐피리디닐아미노-2,4-디플루오로페닐 설폰아미드 유도체는 B-raf 키나제의 활성을 효과적으로 조절하므로 Raf 키나제의 과활성에 의해 유발되는 질환인 암, 그중에서도 다양한 흑색종, 대장암, 전립선암, 감상선암, 난소암 등의 예방 또는 치료에 유용하게 사용될 수 있다.