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English

This abnormality manifests in different ways (Figure 5) that include serious anomalies in the brain and facies, mainly associated to the midline, such as cyclopia, ethmocephaly, cebocephaly, cleft lip and/or cleft palate, ocular hypotelorism and hypertelorism (4, 8, 9, 10).

Spanish

5), que involucran graves anomalías en el cerebro y las facies, asociadas principalmente con la línea media, como ciclopía, etmocefalia, cebocefalia, fisura labial y/o palatal mediana, hipotelorismo e hipertelorismo ocular (4, 8, 9, 10).