Metadata
Author: springer
Data
English[en]
By using the 3- and 6-month-old Alzheimer’s model mice (AD-1) as the experimental models, our observations demonstrate that zinc gluconate molecules could pass through the blood–brain barrier and then produce hippocampus region-specific accumulation of fluorescent zinc nanoclusters in vivo, thus allowing kinetically controlled selective imaging of AD by fluorescence bio-imaging.
Chinese[zh]
研究结果表明,葡萄糖酸锌可以通过阿尔兹海默症模型鼠的血脑屏障,富集于病变的海马区并实现对于阿尔兹海默症的精确标记与实时动态靶向荧光成像。