Besonderhede van voorbeeld: -8969023755887760938

Metadata

Author: patents-wipo

Data

English[en]
The novel blocker for vascular leakage of the present invention inhibits the apoptosis of endothelial cells, suppresses the formation of actin stress fibers induced by VEGF, and increases the structure of the cortical actin ring, thereby inhibiting vascular leakage.
French[fr]
Le nouveau bloquant contre les fuites vasculaires de la présente invention inhibe l'apoptose des cellules endothéliales, supprime la formation de fibres de stress actine induite par le VEGF, et épaissit la structure de l'anneau d'actine corticale, inhibant ainsi les fuites vasculaires.
Korean[ko]
본 발명은 신규한 혈관누출 차단제에 관한 것으로서, 본 발명의 신규한 혈관누출 차단제는 혈관내피세포의 사멸을 억제하고, VEGF에 의해 유도된 액틴 스트레스 파이버의 형성을 억제하고 외피 액틴 링(cortical actin ring)의 구조를 증가시켜 혈관 누출을 억제한다.

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