Metadata
Author: scielo-abstract
Data
English[en]
Apples are a rich source of Procyanidins (Pcy) which are able to inhibit colon carcinogenesis in animal models, but the mechanisms through which this occurs are not well understood.The evidence obtained in our laboratory and by other researchers, which shows that Pcy trigger apoptosis through different mechanisms in human colon adenocarcinoma SW480 cells and their derived-metastatic SW620 cells is reviewed in this paper.
Spanish[es]
Las manzanas son fuente rica en Procianidinas (Pcy), inhiben la carcinogénesis del colon en modelos animales aunque los mecanismos no son bien comprendidos. Esta revisión presenta evidencia sobre los efectos pro-apoptóticos de Pcy por diferentes mecanismos en células humanas de adenocarcinoma de colon SW480 y sus derivadas metastáticas SW620.