Metadata
Author: WikiMatrix
Data
English[en]
Pioneering work by Noel Rose and Ernst Witebsky in New York, and Roitt and Doniach at University College London provided clear evidence that, at least in terms of antibody-producing B cells (B lymphocytes), diseases such as rheumatoid arthritis and thyrotoxicosis are associated with loss of immunological tolerance, which is the ability of an individual to ignore "self", while reacting to "non-self".
Galician[gl]
Os traballos pioneiros de Noel Rose e Ernst Witebsky en Nova York, e de Roitt e Doniach en Londres proporcionaron claras evidencias de que, polo menos para os linfocitos B produtores de anticorpos, enfermidades como a artrite reumatoide e a tirotoxicose están asociadas coa perda da tolerancia inmunolóxica, que é a capacidade do sistema inmunitario dun individuo de ignorar o propio e reaccionar contra o non propio.