Metadata
Author: patents-wipo
Data
English[en]
The present invention provides L-arginine salts of 4-ammosalicylic acid and 5-ammosalicylic acid (mesalamine) Pharmaceutical compositions containing these L-argmme salts are useful for the treatment of inflammatory conditions of the gastrointestinal (GI) tract such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) The compositions may be used to treat Crohn's disease, gastritis, celiac disease, peptic ulcer disease, inflammatory conditions of the mouth and esophagus, pre-cancerous lesions of the stomach, non-ulcer dyspepsia, bacterial overgrowth, peptic ulcer disease, fissures of the intestine, ulcerative colitis, infectious colitis, precancerous conditions of the colon, proctitis, inflammation associated with hemorrhoids, protalgia fugax, rectal fissures, and liver gallbladder and/or bilary tract conditions.
French[fr]
L'invention concerne des sels L-arginine d'acide 4- ou 5-aminosalicylique, et une composition pharmaceutique contenant ces sels L-arginine d'acide 4- ou 5-aminosalicylique en tant qu'ingrédients actifs, utiles dans le traitement d'une condition inflammatoire de la voie gastro-intestinale telle qu'une maladie intestinale inflammatoire et le côlon irritable.