Metadata
Author: scielo-abstract
Data
English[en]
In order to examine possible interactions related with: endothelium, nitric oxide (NO), guanylyl ciclasa, prostanoid or ATP dependent potassium (K+ATP) channels, the compounds with greater relaxant effect: 3-O-methylquercetin, and 3,7-di-O-methylquer-cetin, were assessed in phenylephrine precontracted rings in presence or absence of: endothelium, L-NAME (G -nitro-L-Arginine-Methyl Ester, 100 μM), ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, 1 μM), sodium meclofenamate (10 μM) or glibenclamide (1 μM).
Spanish[es]
Para examinar posibles interacciones con endotelio, óxido nítrico, guanilato ciclasa, prostanoides o canales de K+ATP, aquéllos con mayores efectos vasodilatadores: 3-O-metilquercetina y 3,7-di-O-metilquercetina, se evaluaron en anillos estimulados con fenilefrina en presencia o ausencia de: endotelio, L-NAME (G -nitro-L-Arginina-Metil Ester, 100 μM), ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-ona, 1 μM), meclofenamato sódico (10 μM) o glibenclamida (1 μM).