Metadata
Author: springer
Data
German[de]
Die Charakterisierung der vier DCM-Formen erfolgt mit den serologischen Biomarkern der Herzinsuffizienz (BNP, NTproBNP), der Nekrose (Troponine) und der Fibrose (MMPs und TIMPs), mit nichtinvasiver Bildgebung (Echokardiographie, Doppler/TDI, Kardio-MRT) und invasiver Katheterdiagnostik einschließlich Koronarangiographie und Endomyokardbiopsie.
English[en]
The role of specific diabetic drivers to the clinical phenotypes, to macro- and microangiopathy as well as accompanying risk factors or confounders, e.g. hypertension, autoimmune factors or inflammation with or without viral persistence, need to be identified in each individual patient separately. Thus hyperglycemia, hyperinsulinemia and insulin resistance as well as lipotoxicity by free fatty acids (FFAs) are the factors responsible for diabetic cardiomyopathy.