Metadata
Author: patents-wipo
Data
English[en]
The monoacetyldiacylglycerol compound of the present invention inhibits the expression of IL-4 in EL-4 cells, which are mouse T cell lymphoma cells, reduces hypersensitivity of airway in an asthma-induced animal model, and inhibits the infiltration of inflammatory cells into the bronchial tube.
French[fr]
Le composé de monoacétyldiacylglycérol selon l’invention inhibe l’expression de l’IL-4 dans les cellules EL-4, lignée cellulaire de lymphome T chez la souris, réduit l’hypersensibilité des voies respiratoires chez le modèle animal chez qui l’asthme est induit, et inhibe l’infiltration des cellules inflammatoires dans les bronches.
Korean[ko]
본 발명의 모노아세틸디아실글리세롤 화합물은, 생쥐 T 세포 림프종 세포인 EL-4 세포에서 IL-4의 발현을 억제하고, 천식유발 동물모델에서 기도과민성을 경감시키며, 기관지 내 염증세포 침윤을 억제한다.