ethinylestradiol oor Sjinees
ethinylestradiol
en
A derivative of 17β-estradiol, the major endogenous estrogen in humans, used in oral contraceptives.
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炔雌醇
en
chemical compound
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voorbeelde
Advanced filtering
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It is used alone in progestogen-only pills ("mini pills") and in combination with the estrogen ethinylestradiol in combined oral contraceptive pills.
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Separately, the EMA conducted a review on the use of Diane 35 (cyproterone acetate 2 mg, ethinylestradiol 35 micrograms) and its generics.
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Medications cited specifically in the petition include Apri-28, Cyclessa, Desogen, Kariva, Mircette, Ortho-Cept, Reclipsen, Velivet, and some generic pills, all of which contain desogestrel in combination with ethinylestradiol.
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Desogestrel also reduces sex hormone-binding globulin (SHBG) levels by 50% when given to women alone, but when combined with 30 μg/day ethinylestradiol, which in contrast strongly activates SHBG production, there is a 200% increase in SHBG concentrations.
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In addition, acne and hirsutism are negligible when combined with ethinylestradiol, and this combination can actually be used to treat such symptoms.
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In the United States, it is available only in combination with ethinylestradiol as a combined oral contraceptive; it is not available alone and is not approved for any other indications in this country.
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Medications containing desogestrel as the only active ingredient (as opposed to being used in conjunction with ethinylestradiol, like in combined oral contraceptives) do not show an increased thrombosis risk and are therefore safer than second-generation birth-control pills in regards to thrombosis.
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Interference with enterohepatic circulation: Some clinical reports suggest that enterohepatic circulation of estrogens may decrease when administered some antibiotics, which may reduce ethinylestradiol concentrations (eg penicillins, tetracyclines).
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8 sinne gevind in 2 ms. Hulle kom uit baie bronne en word nie nagegaan nie.