antiviral drugs — toxicity oor Duits
antiviral drugs — toxicity
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antivirale Medikamente — Toxizität
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The antiretroviral activity, tolerance and toxicity of two different antiviral drug combinations were assessed and compared in a randomized, crossover pilot study in 16 HIV-1 p24 antigenaemic subjects with asymptomatic HIV infection.
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CMV prophylaxis with certain existing antivirals has been associated with drug-specific effects, including myelosuppression and renal toxicity, in HSCT recipients.
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Interestingly, micronutrients were more effective than the popular antiviral flu drug, Tamiflu, and of course do not have the dangers of toxicity associated with it.
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CMV prophylaxis with certain existing antivirals has been associated with drug-specific effects, including myelosuppression and renal and bone marrow toxicity, in HSCT recipients.
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Currently, there is no approved treatment available to prevent recurrence of the hepatitis C virus after transplant surgery since current antiviral regimens are generally not used due to toxicities, tolerability issues and drug-drug interactions minimum within the first 6 months after transplantation.
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Currently, there is no approved treatment available to prevent recurrence of the Hepatitis C virus after surgery since current antiviral regimens can not be safely used after surgery due to toxicities, tolerability issues and drug-drug interactions within the first months after transplantation.
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Aims of this study were to characterize interactions of HDV and the innate immune system, to investigate the persistence and cell toxicity of an HDV mono-infection and to determine effects of different antiviral drugs on HDV productivity by establishing and using a novel assay to quantify genomic and antigenomic HDV RNA.
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These preclinical research services are part of the ImQuestSUCCESS Platform and include compound screening to define compound efficacy and drug target validation to define the mechanism of action and toxicity of pharmaceutical products, as well as evaluation of the potential of products to induce resistance and the impact of combination antiviral therapy.
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