mitoxantrone oor Grieks
mitoxantrone
en
A particular drug used in chemotherapy.
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μιτοξανδρόνη
en
particular drug used in chemotherapy
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More dangerous but much less common are liver damage from interferons, systolic dysfunction (12%), infertility, and acute myeloid leukemia (0.8%) from mitoxantrone, and progressive multifocal leukoencephalopathy occurring with natalizumab (occurring in 1 in 600 people treated).
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Mitoxantrone, whose use is limited by severe adverse effects, is a third-line option for those who do not respond to other medications.
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Patients who received docetaxel every three weeks demonstrated significantly longer overall survival compared to those treated with mitoxantrone
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The increase in survival seen in the docetaxel weekly arm was not statistically significant compared to the mitoxantrone control arm
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In a clinical trial in which Zevalin was administered as consolidation after prior first line chemotherapy a higher frequency of severe and prolonged neutropenia and thrombocytopenia was observed in patients who had received Zevalin within # months after a combination chemotherapy of fludarabine with mitoxantrone and/or cyclophosphamide compared to those patients who had received any other chemotherapy
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Patients with increased risk for opportunistic infections, including immunocompromised patients (including those currently receiving immunosuppressive therapies or those immunocompromised by prior therapies, e. g. mitoxantrone or cyclophosphamide, see also sections # and
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Patients with a treatment history of immunosuppressant medications, including cyclophosphamide and mitoxantrone, may experience prolonged immunosuppression and therefore may be at increased risk for PML
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Key Words: Multiple Sclerosis, Immunosuppressive Treatment; Chemotherapeutic; Mitoxantrone; Cyclophosphamide.
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As of 2011[update], only one medication, mitoxantrone, has been approved for secondary progressive MS.[84] In this population tentative evidence supports mitoxantrone moderately slowing the progression of the disease and decreasing rates of relapses over two years.
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As of 2011[update], only one medication, mitoxantrone, has been approved for secondary progressive MS.[86] In this population tentative evidence supports mitoxantrone moderately slowing the progression of the disease and decreasing rates of relapses over two years.[87][88] Adverse effects
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No treatment has been shown to change the course of primary progressive MS[8] and as of 2011 only one medication, mitoxantrone, has been approved for secondary progressive MS.[73] In this population tentative evidence supports mitoxantrone moderately slowing the progression of the disease and decreasing rates of relapses over two years.[74][75]
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Azathioprine, methotrexate, cyclosporine, mycophenolate mofetil, mitoxantrone, cyclophosphamide and rituximab are the most utilized agents.
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12 sinne gevind in 5 ms. Hulle kom uit baie bronne en word nie nagegaan nie.