In vitro metabolism data and the human mass balance study results indicated that the cytochrome P450 system is not involved in the metabolism of decitabine.
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In-vitro studies on dexrazoxane in human microsomes have shown high stability of dexrazoxane indicating that major metabolism via cytochrome P450 is unlikely.
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Human liver microsomes are ideal system for monitoring the metabolic activity because cytochrom P450 enzymes are linked to membranes of endoplasmatic reticulum and are expressed in liver.
I koristi se.- Pa kako je onda koristiš za lomljavu?ParaCrawl Corpus ParaCrawl Corpus
In humans, porphyrins are the main precursors of heme, an essential constituent of hemoglobin, myoglobin, catalase, peroxidase, respiratory and P450 liver cytochromes.
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