purine oor Indonesies
purine
en
(chemistry) Any of a class of organic heterocyclic base containing fused pyrimidine and imidazole rings; they are components of nucleic acids
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Purina
en
chemical compound
id
senyawa kimia
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In some animals, and in humans, the oxidation of xanthine to uric acid, a process of purine catabolism, is catalyzed by xanthine oxidase, a molybdenum-containing enzyme.
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Two of the four deoxyribonucleotides (deoxyadenosine and deoxyguanosine) and two of the four ribonucleotides (adenosine, or AMP, and guanosine, or GMP), the respective building blocks of DNA and RNA, are purines.
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Oro, Orgel and co-workers have shown that four molecules of HCN tetramerize to form diaminomaleodinitrile (12), which can be converted into almost all naturally-occurring purines.
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Purines are found in high concentration in meat and meat products, especially internal organs such as liver and kidney.
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Purines are biologically synthesized as nucleosides (bases attached to ribose).
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A small molecule dubbed reversine, a purine analog, has been discovered that has proven to induce dedifferentiation in myotubes.
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According to an article published in Australian Doctor, the consumption of purine-rich mushrooms and vegetables, such as beans, lentils, peas, spinach, and cauliflower, “has not been shown to be associated with a similar increased risk of acute gout.”
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Three nucleobases found in nucleic acids, cytosine (C), thymine (T), and uracil (U), are pyrimidine derivatives: In DNA and RNA, these bases form hydrogen bonds with their complementary purines.
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In the United States, consumption of added 5'-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines.
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Nevertheless, some authorities also recommend cutting back on foods that contain high amounts of purines, such as yeast, certain fish, and various red meats.
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These include: folic acid analogues, such as methotrexate purine analogues, such as azathioprine and mercaptopurine pyrimidine analogues, such as fluorouracil protein synthesis inhibitors.
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The word purine (pure urine) was coined by the German chemist Emil Fischer in 1884.
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In 1884, Hermann Emil Fischer proposed the structure of purine, a key structure in many biomolecules, which he later synthesized in 1898.
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Many organisms have metabolic pathways to synthesize and break down purines.
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Purine (1) is obtained in good yield when formamide is heated in an open vessel at 170 °C for 28 hours.
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However, an extremely high concentration of molybdenum reverses the trend and can act as an inhibitor in both purine catabolism and other processes.
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Dacarbazine is in the alkylating agent and purine analog families of medication.
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It is nonenzymatically cleaved to mercaptopurine, that acts as a purine analogue and an inhibitor of DNA synthesis.
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Disodium guanylate is not safe for babies under twelve weeks, and should generally be avoided by asthmatics and people with gout, as guanylates are metabolized to purines.
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Uric acid is a waste product circulating in the blood, and it results from the breakdown of substances called purines.
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1884 Hermann Emil Fischer proposes structure of purine, a key structure in many biomolecules, which he later synthesized in 1898.
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Obesity and diet: The Encyclopedia of Human Nutrition states: “Dietary management of gout no longer seems to be focused on restriction of foods with a high purine content but, rather, on the treatment of metabolic disorders commonly associated with gout: obesity, insulin resistance syndrome, and dyslipidemia,” or abnormal blood levels of lipids, such as cholesterol.
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The product was reduced to purine (1) using zinc dust.
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Similarly, when in its amastigote stage, Leishmania obtains all its purine sources, various vitamins, and a number of its essential amino acids from the phagolysosome of its host.
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24 sinne gevind in 3 ms. Hulle kom uit baie bronne en word nie nagegaan nie.