The gold nanoparticles (GI-Au NPs, PI-AU NPs) which have been surface-treated with phytochemicals according to the present invention exhibit no cytotoxicity, have a superior antioxidant effect, have a superior skin-regenerating effect due to the suppression of skin cell collagen cleaving enzymes (MMP-1 and MMP-8), and have a superior superoxide dismutase (SOD) activity and thus a superior degree of antioxidation in skin cells, and therefore may be useful as a cosmetic composition for preventing skin aging.
본 발명에 따른 파이토케미컬로 표면처리된 금나노입자(GI-Au NPs, PI-Au NPs)는, 세포독성이 없고, 항산화 효과가 우수하며, 피부세포의 콜라겐 분해효소(MMP-1 및 MMP-8)를 억제하여 피부재생능력이 우수하고, 과산화 억제효소(SOD) 활성이 우수하여 피부세포 항산화도가 우수함으로, 피부노화방지용 화장료 조성물에 유용하게 사용될 수 있다.patents-wipo patents-wipo