Balsa lipídica oor Engels

Balsa lipídica

Vertalings in die woordeboek Galisies - Engels

membrane raft

Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and pro

voorbeelde

Parte 2: Balsas lipídicas como principio organizador das membranas Parte 3: Bioxénese de membranas apicais ricas en glicolípidos
Part 2: Lipid rafts as a membrane organizing principle Part 3: Biogenesis of glycolipid-rich apical membranes

Un segundo argumento cuestiona a efectividade do deseño experimental cando se alteran as balsas lipídicas.
A second argument questions the effectiveness of the experimental design when disrupting lipid rafts.

A manipulación do colesterol é unha das técnicas máis amplamente utilizada no estudo das balsas lipídicas.
Manipulation of cholesterol is one of the most widely used techniques for studying lipid rafts.

O procesamento amiloidoxénico da APP foi ligado á súa poresenza en balsas lipídicas.
The amyloidogenic processing of APP has been linked to its presence in lipid rafts.

A actividade de gamma-secretase foi tamén asocidada con balsas lipídicas.
Gamma secretase activity has also been associated with lipid rafts.

As balsas lipídicas son pequenos microdominios cun tamaño entre 10–200 nm.
Lipid rafts are small microdomains ranging from 10–200 nm in size.

Na membrana plasmática, unha forma de compartimentalización é a utilización de balsas lipídicas.
In the plasma membrane, one approach of compartmentalization utilizes lipid rafts.

Outras técnicas utilizadas na análise bioquímica das balsas lipídicas son a ELISA, western blot, e FACS.
Other techniques used in the analysis of lipid rafts include ELISA, western blotting, and FACS.

Propuxéronse dous tipos de balsas lipídicas: balsas lipídicas planares (tamén chamadas non caveolares ou glicolipídicas) e caveolas.
Two types of lipid rafts have been proposed: planar lipid rafts (also referred to as non-caveolar, or glycolipid, rafts) and caveolae.

A depleción do colesterol nas balsas lipídicas inhibe a infección por EV1.
Depletion of cholesterol in lipid rafts inhibits EV1 infection.

As probas acumuladas apoian que os virus entran nas células utilizando microdominios de memrbana específicos, incluíndo balsas lipídicas.
Accumulated evidence supports that viruses enter cells via penetration of specific membrane microdomains, including lipid rafts.

Se as balsas lipídicas existen, poderían formarse só nunha escala de tempo que fose irrelevante para os procesos biolóxicos.
If lipid rafts exist, they may only occur on a time scale that is irrelevant to biological processes.

Unha diferenza clave entre as balsas lipídicas e as membranas plasmáticas das que derivan é a súa composición en lípidos.
One key difference between lipid rafts and the plasma membranes from which they are derived is lipid composition.

O sarcolema tamén contén caveolas, que son microdominios de balsas lipídicas especializados en eventos de sinalización celular e canais iónicos.
The sarcolemma also contains caveolae, which are microdomains of lipid rafts specialized to cell signaling events and ion channels.

Ademais, as balsas lipídicas están enriquecidas en esfingolípidos como a esfingomielina, que está tipicamente elevada nun 50% en comparación coa membrana plasmática.
Also, lipid rafts are enriched in sphingolipids such as sphingomyelin, which is typically elevated by 50% compared to the plasma membrane.

Pike e Miller discuten os inconvenientes potenciais que ten o uso da depleción de colesterol para determinar a función das balsas lipídicas.
Pike and Miller discuss potential pitfalls of using cholesterol depletion to determine lipid raft function.

Crese que a unión a este dominio tamén facilita a reinternalización da proteína ao incrementar a súa afinidade a balsas lipídicas endocíticas.
Binding to this domain is also thought to facilitate the re-internalization of the protein by increasing its affinity to endocytotic lipid rafts.

Rietveld & Simons relacionaron as balsas lipídicas de membranas modelo coa inmiscibilidade de fases líquidas ordenadas (fase Lo) e desordenadas (fase Ld ou Lα).
Rietveld & Simons related lipid rafts in model membranes to the immiscibility of ordered (Lo phase) and disordered (Ld or Lα phase) liquid phases.

Non hai consenso sobre o tamaño das balsas lipídicas, e os informes achegados dan diversos valores situados no intervalo entre 1 e 1.000 nanómetros.
Second, there is no consensus on lipid raft size, which has been reported anywhere between 1 and 1,000 nanometers.

Debido a que o seu tamaño está debaixo do límite clásico de difracción dun microscopio óptico, as balsas lipídicas son difíciles de visualizar directamente.
Due to their size being below the classical diffraction limit of a light microscope, lipid rafts have proved difficult to visualize directly.

Os que formulan argumentos en contra da existencia das balsas lipídicas indican os seguintes: Debería existir unha tensión entre as fases Lα and Lo.
Arguments against the existence of lipid rafts include the following: First, a line tension should exist between the Lα and Lo phases.

O motivo rico en prolina C-terminal de CD28 é importante para traer Lck e balsas lipídicas á sinapse inmune por medio de filamina-A.
The C-terminal proline-rich motif in CD28 is important for bringing Lck and lipid rafts into the immune synapse via filamin-A.

As caveolas, por outra parte, son invaxinacións arredondadas da membrana plasmática que conteñen proteínas caveolinas e son as estruturas máis facilmente observables entre as balsas lipídicas.
Caveolae, on the other hand, are flask shaped invaginations of the plasma membrane that contain caveolin proteins and are the most readily-observed structures in lipid rafts.

Unha hipótese é que a ceramida xerada na membrana plasmática estabiliza pequenas plataformas lipídicas denominadas balsas lipídicas, permitíndolles que sirvan como plataformas para a sinalización de moléculas.
One hypothesis is that ceramide generated in the plasma membrane enhances membrane rigidity and stabilizes smaller lipid platforms known as lipid rafts, allowing them to serve as platforms for signalling molecules.

Pénsase que isto se debe a que está localizado diferencialmente na membrana plasmática, mentres que o TrkA e o TrkC están colocalizadas con p75NTR en balsas lipídicas.
This is thought to be because it is differentially located in the cell membrane while TrkA and TrkC are co-localized with p75NTR in lipid rafts.