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second-line treatment
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Nplate may be considered as second line treatment for adult non-splenectomised patients where surgery is contra-indicated
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If it is not effective, a second-line treatment is given.
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Hence, the significant benefit at the initial marketing authorisation stage may be limited to second-line treatment.
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As of January # countries have adopted artemisinin-based combination therapies as their first or second line treatment choice
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Second-line treatment approaches include phototherapy (narrow band UVB or UVA1) and extracorporeal photopheresis.
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(c) Use of lindane as a second-line treatment only;
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· Use of Lindane as a second-line treatment only;
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• Is combination chemotherapy superior to single-agent chemotherapy in second-line treatment?
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Metastatic breast and ovarian cancer (second-line treatment
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The median duration of second-line treatment with Glivec was # months
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· Use of Lindane as a second-line treatment only;
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Second line treatment may include fludarabine, combined with cyclophosphamide and/or mitoxantrone, usually with rituximab.
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Second-line treatments are less effective, more costly, more toxic, and sometimes extremely difficult to administer.
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In 2015, only 1in 5 of the people newly eligible for second-line treatment were able to access it.
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As regards, in particular, sertindole, ECG monitoring and second line treatment were, according to the applicant, accepted as RMMs.
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Subpopulations analyzed: second line treatment (base case), second and third-line (ECOG 0–1 or not) and third-line only.
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As of January 2006, 56 countries have adopted artemisinin-based combination therapies as their first or second line treatment choice.
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He stressed that drug pricing was still an issue - to ensure that both first-line and second-line treatments were affordable.
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As recommended by # countries # of them in Africa- have adopted artemisinin-based combination therapies as their first or second-line treatment
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However, not all countries have adopted low cost regimens as their standard and the cost of second line treatment remains high.
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