Le composé (I) peut être utilisé pour traiter et prévenir des maladies cardiovasculaires telles que l'angine de poitrine stable et instable, l'angor de Prinzmetal (spasme), le syndrome coronarien aigu, l'insuffisance cardiaque, l'infarctus du myocarde, l'accident vasculaire cérébral, la thrombose, la maladie occlusive artérielle périphérique (PAOD), l'athérosclérose, la resténose, les lésions endothéliales après ACTP, l'hypertension essentielle, l'hypertension pulmonaire, l'hypertension secondaire, la glomérulonéphrite chronique rénovasculaire, la dysérection et l'arythmie ventriculaire.
The compound (I) can be used for the therapy and prophylaxis of cardiovascular diseases like stable and unstable angina pectoris, Prinzmetal angina (spasm), acute coronary syndrome, heart failure, myocardial infarction, stroke, thrombosis, peripheral artery occlusive disease PAOD, atherosclerosis, restenosis, endothel damage after PTCA, essential hypertension, pulmonary hypertension, secondary hypertension, renovascular chronic glomerulonephritis, erectile dysfunction, ventricular arrhythmia, and the lowering of cardiovascular risk of postmenopausal women or after intake of contraceptiva, the therapy and propylaxis of diabetes and diabetes complications (nephropathy, retinopathy), angiogenesis, asthma bronchiale, chronic renal failure, cirrhosis of the liver, restricted memory performance or a restricted ability to learn.patents-wipo patents-wipo