hepatic microsome oor Spaans
hepatic microsome
Vertalings in die woordeboek Engels - Spaans
microsoma hepático
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In hepatic microsomes, cytochromes P450 can comprise as much as 20% of the total protein.
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In hepatic microsomes, cytochrome P450s can comprise as much as 20% of the total protein.
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Amide local anesthetics are biotransformed in the liver by hepatic microsomal enzymes.
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Alcohol might increase GGT production by inducing hepatic microsomal production, or it might cause the leakage of GGT from hepatocytes.
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Female mice receiving duloxetine for # years had an increased incidence of hepatocellular adenomas and carcinomas at the high dose only (# mg/kg/day), but these were considered to be secondary to # hepatic microsomal enzyme induction
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Female mice receiving duloxetine for # years had an increased incidence of hepatocellular adenomas and carcinomas at the high dose only (# mg/kg/day), but these were considered to be secondary to hepatic microsomal enzyme induction
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This paper shows a bibliographical review of the studies conducted on the biotransformation of methylone and MDPV using in vitro models with human hepatic microsomes, cell fractions S9 and in vivo models in animals with posterior analysis of the obtained metabolites.
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The latter is due to decreased activity of microsomal enzymes and reduced hepatic perfusion with aging.
Prueba este puréLiterature Literature
Carbaryl is a weak inducer of hepatic microsomal drug-metabolizing activity. Phenobarbital sleeping time is shortened.
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Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes.
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Interaction with other drugs: Chloramphenicol inhibits hepatic microsomal enzymes that metabolize several drugs.
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Because neonates have partially developed hepatic microsomal enzyme systems, they also have difficulty metabolizing many drugs.
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Creosote has been shown to be a hepatic microsomal enzyme inducer in laboratory mammals.
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Carbaryl is a weak inducer of hepatic microsomal drug-metabolizing activity. It reduces phenobarbital sleeping time.
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An in vitro study indicated that HCFC 141b is dechlorinated to a limited extent by hepatic microsomes.
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MIBK was capable of increasing liver weight (at > 1025 mg/m3 (250 ppm)) and inducing hepatic microsomal metabolism.
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The importance of the hepatic microsomal nitroreductase-mediated nitro group reduction for the mutagenic activity of nitroimidazols has been studied.
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Phenytoin, phenobarbital, primidone, or phenothiazines In most patients, cause folate (folic acid) deficiency*, probably because hepatic microsomal drug-metabolizing enzymes are affected
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Consistently, FireMaster(R) was found to be a mixed-type inducer of hepatic microsomal enzymes in rats, as well as in all other animal species tested.
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In children as in adults, antiepileptic drugs that induce hepatic microsomal enzymes cause a reduction in the concentration of topiramate in the plasma and increase the degree of its metabolism.
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The plasma half-life progressively shortens by ~40% during the first 2 wk of treatment because of the induction of hepatic microsomal enzymes; conversely, it is increased with hepatic dysfunction.
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35 sinne gevind in 12 ms. Hulle kom uit baie bronne en word nie nagegaan nie.