spastic paraparesis oor Portugees
spastic paraparesis
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paraparesia espástica
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It is characterized by spastic paraparesis with minimal sensory and sphincteric involvement.
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Human T-lymphotropic virus type 1 (HTLV-1) infection and spastic paraparesis.
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The patient was diagnosed with myelopathy associated with HTLV-1/tropical spastic paraparesis and treated with interferon beta-1a.
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SUMMARY Human T-lymphotropic virus type 1 (HTLV-1) causes disorders such as chronic inflammatory progressive myelopathy, which is known as HTLV-1associated myelopathy (MAH), characterized by spastic paraparesis symptoms.
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In addition to causing a form of adult leukemia, the virus has also been linked to a nerve disease —tropical spastic paraparesis, or TSP— that is similar to multiple sclerosis.
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The disease was clinically established as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and laboratory tests confirmed the presence of antibodies to HTLV-1 in the cerebrospinal fluid (CSF). Mumps, cytomegalovirus, Epstein-Barr virus, schistosomiasis, herpes virus 1 and 2, rubella, measles, varicella-zoster toxoplasmosis, hepatitis, HIV, and syphilis were excluded by serology.
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This review, carried out through systematic search of databases, compiles the most outstanding information about this retrovirus and the spastic paraparesis, provides basic knowledge on the disease, illustrates on an unknown health problem and creates the need for early diagnosis in order to stop the chain of viral infection and prevent its silent propagation among the population.
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Palabras clave: spastic paraparesis; HTLV-1; pathogenesis; epidemiology; confirmatory studies; donor control.
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CD4+ T cell subsets changes in HTLV-1-infected subjects with tropical spastic paraparesis...
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Tropical spastic paraparesis (TSP) is a chronic degenerative neurological disease associated with this infection.
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· Spastic paraparesis by HTLV-I: 20 years later.
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The HTLV-1 is associated to a progressive presentation of spastic paraparesis.
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An autosomal dominant familial prion disease with a wide spectrum of clinical presentations including ataxia, spastic paraparesis, extrapyramidal signs, and dementia.
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Two major diseases are related to this virus adult T cell leukemia (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
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HTLV-I has been associated with a chronic idiopatic spastic paraparesis (CHISPA) in man; however, a complete understanding of this association is still debated.
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The diagnosis of tropical spastic paraparesis/HTLV-1–associated myelopathy is usually based on symptoms and the person’s risk of being exposed to the virus.
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The main HTLV-1-associated diseases are the HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and the adult T cell leukemia/lymphoma (ATL)....
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Two major pathologies has been associated with HTLV-1 infection: adult T- cell leukemia/lymphoma (ATLL) and HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM / TSP).
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However, a low number of individuals with tropical spastic paraparesis and associated myelopahy to the HTLV-I (TSP/HAM) show immunopathologic characteristics as T lymphocytes proliferation.
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izabela_stmAbstract Human T-lymphotropic virus 1 (HTLV-1) is associated with Tropical Spastic Paraparesis / HTLV-1 Associated Myelopathy (HAM / TSP), a disease characterized by slow and progressive evolution.
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A case of spastic paraparesis associated with HTLV-I retrovirus was described in a 34-year-old patient whose diagnosis was made 17 years after the onset of his disease.
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In addition to the well-known association between HTLV-1 and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), several diseases and neurologic manifestations have been associated with the virus.
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Resumen: The HTLV-1 was first described retroviruses associated with human diseases, such as leukemia adult T cell (ATLL), tropical spastic paraparesis / HTLV-associated myelopathy (TSP / HAM), infective dermatitis, among others.
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INTRODUCTION: the HTLV-1 is a human retrovirus associated with adult T-cell leukaemia (ATL) and with HTLV-1- associated myelopathy or tropical spastic paraparesis, which has also been implicated in the development of autoimmunity.
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Syrinx of the Spinal Cord and Brain Stem Tropical Spastic Paraparesis/HTLV-1–Associated Myelopathy Causes of spinal cord disorders include injuries, infections, a blocked blood supply, and compression by a fractured bone or a tumor.
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