The invention relates to a method, to a device, and to uses for directly analyzing samples by means of HPLC, wherein the sample, which contains at least one analyte, is applied in liquid form to a sample carrier (3) and dried, such that the sample is present on the sample carrier (3) in the form of a dried spot, clamped in a pressure-tight manner between two adapters (7, 9) of an adapter system (1), wherein each of the adapters (7, 9) has a central cavity (19, 21) in the direction of the clamped sample, into which an extraction agent is fed via a feed line (5) in the case of one adapter, and in case of the other adapter, said agent is removed via a discharge line (11), and, in the process, said agent flows through the clamped sample carrier (3), and the sample is washed out of the sample carrier (3).
Die Resorptionsrate wurde beeinflusst, so dass die Cmax um # % verringert und die Tmax um # Stunden verlängert wurdepatents-wipo patents-wipo