Disclosed is a single needle integrated artificial pancreas, wherein the single needle integrated artificial pancreas comprises a drug reservoir unit (1); a dosing drive unit (2) connected to the drug reservoir unit (1); an indwelling unit (3) connected to the drug reservoir unit (1) and comprising a glucose sensor (31), an insulin-indwelling hose (32), a puncture needle (33) and a mounting means (34), wherein the glucose sensor (31) and the insulin-indwelling hose (32) are simultaneously implanted in the same subcutaneous tissue in a patient via the mounting means (34) under the aid of the puncture needle (33), and the puncture needle (33) is a puncture steel needle or groove puncture needle; and a blood glucose monitoring and insulin administration control unit (4) is respectively connected to the drug reservoir unit (1), the dosing drive unit (2) and the indwelling unit (3).
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