Tracing the zoonotic origins of HCoVs provides a framework to understand the natural history, driving force and restriction factors of species jumping.
(Matthew 4:23) Understandably, multitudes followed him, and “all the crowd were seeking to touch him, because power was going out of him and healing them all.”
Continuous surveillance in mammals is necessary for better understanding of the ecology of CoVs and their natural hosts, which will prove useful in preventing animal-to-human transmission and future outbreaks.